Malegra 200mg contains the active ingredient sildenafil citrate, which belongs to a class of medications known as phosphodiesterase type 5 (PDE5) inhibitors. To understand how Malegra 200mg works, it’s important to grasp the physiological process of an erection.

During sexual arousal, the release of nitric oxide in the erectile tissue of the penis triggers the production of a chemical called cyclic guanosine monophosphate (cGMP). cGMP is responsible for relaxing the smooth muscles in the blood vessels of the penis (corpora cavernosa), allowing them to widen and increase blood flow.

However, an enzyme called phosphodiesterase type 5 (PDE5) naturally breaks down cGMP. This can lead to a reduction in blood flow and an inability to maintain an erection.

Malegra 200mg works by inhibiting the action of PDE5. By doing so, it helps to prolong the effects of cGMP, allowing for increased blood flow to the penis. This improved blood flow facilitates and sustains an erection when the man is sexually aroused.