Because when you look closely at your relationship to food, other habits tend to surface. So, although detoxing for many is triggered by a wish to lose weight, it can be much more than that. About the size of a football, it's located mainly in the upper right portion of your abdomen — beneath the diaphragm and above your stomach — but a small portion extends into the upper left quadrant. Professional ServicesExplore Mayo Clinic's many resources and see jobs available for medical professionals. Quality CareFind out why Mayo Clinic is the right place for your health care. Rob Hobson is a registered nutritionist , published author and food writer.